Publication

PUBLICATIONS

Selected Publications

1. Gita Kumari, P. K. Singhal, M.R.K., Subba Rao, and S. Mahalingam. (2007). Nuclear Transport of Ras Associated Tumor Suppressor Proteins: Different Receptor Binding Specificities for Arginine-rich Nuclear Targeting Signals. Journal of Molecular Biology. 367: 1294-1311.

2. Subba Rao, M.R.K., Gita Kumari., D. Balasundaram., R. Sankaranarayanan and S.Mahalingam. (2006). A Novel Lysine-rich domain and GTP Binding Motifs Regulates the Nucleolar Retention of Human Guanine Nucleotide Binding Protein, GNL3L. Journal of Molecular Biology. 364: 637-654.

3. Singhal,P. K., P. Rajendra Kumar., M. R. K. Subba Rao and S. Mahalingam (2006). Nuclear Export of Simian Immunodeficiency Virus Vpx Protein. Journal of Virology. 80: 12271-12282.

4. Singhal, P.K., Rajendra Kumar. P., Subba Rao. M.R.K., Kyasani. M., and Mahalingam. S. (2006). Simian Immunodeficiency Virus Vpx is imported into the nucleus via importin alpha dependent and independent pathways. Journal of Virology. 80: 526-536.

5. Du.X., Subba Rao. M.R.K., Chen, X.Q., Wei. W., Mahalingam. S, and Balasundaram. D. (2006). The homologous putative GTPases Grn1p from fission yeast and the human GNL3L are required for growth and play a role in processing of nucleolar pre-rRNA. Mol. Biol. Cell. 1: 460-474. 27, 1355, 2006.

6. Varadarajan. P., Mahalingam. S., Gandotra,S, Dorairajoo. D.S., D’souza VM, Balasundarum D. (2005). The functionally conserved nucleoporins Nup124p from fission yeast and the human Nup153 mediate nuclear import and activity of the Tf1 retrotransposon and HIV-1 Vpr. Mol. Biol. Cell 16: 1823-1838. 27, 160, 2006.

7. Rajendra Kumar, P., Singhal, P.K, Subba Rao. M.R.K., and Mahalingam. S. (2005). Phosphorylation by MAPK regulates simian immunodeficiency virus Vpx protein nuclear import and virus infectivity. J. Biol. Chem. 280: 8553-8563. 32, 6335, 2005.

8. Rajendra Kumar, P., Singhal, P.K, Vinod, S.S and Mahalingam. S. (2003). A non-canonical transferable signal mediates nuclear import of simian immunodeficiency virus Vpx protein. Journal of Molecular Biology 331: 1141-1156. 6, 2040, 2005.

9. Mahalingam. S., Van Tine. B., Santiago. M.L., Gao. F., Shaw. G.M., and Hahn. B. (2001). Functional analysis of the Simian Immunodeficiency virus Vpx protein: Identification of packaging determinants and a novel nuclear targeting domain. Journal of Virology. 75: 362-374. 54, 1304, 2005.

10. Mahalingam. S., Ayyavoo. V., Patel. M., Kiebber-Emmons. T., Kao. G.D., Muschel. R.J, and Weiner. D.B. (1998). HIV-1 Vpr interacts with a human 34-mov34 homologue, a cellular factor linked to the G2/M phase transition of the mammalian cell cycle. Proc. Natl. Acad. Sci. USA 95: 3419-3424. 26, 3941, 2005.

11. Ayyavoo. V., Mahboubi. A., Mahalingam. S., Ramalingam. R., Williams. W.V., Sagar. K., Green. D, and Weiner. D.B. (1997). HIV-1 Vpr suppresses immune activation and apoptosis through regulation of NF-kB. Nature Medicine 3: 1117-1123. 26, 3495, 2005.

12. Mahalingam. S., Ayyavoo. V., Patel. M., Kieber-Emmons. T, and Weiner. D.B. (1997). Nuclear import, Virion incorporation and Cell cycle arrest/differentiation are mediated by distinct functional domains of HIV-1 Vpr. Journal of Virology. 71: 6339-6347. 5, 1489, 2004.

13. Kim. J.J., Bagarazzi. M.L., Trivedi. N., Hu. Y., Kazahaya. K., Wilson. D.M., Chattergoon. M.A., Dang. K., Mahalingam.S., Chalian. A.A., Agadjanyan. M.G., Boyer. J.D., Wang. B, and Weiner. D.B. (1997). Engineering of in vivo immune reponses to DNA immunization via codelivery of costimulatory molecule genes. Nature Biotechnology. 15: 641-646. 24, 2205, 2003.

14. Mahalingam. S., Collman. R.G., Patel. M., Monken. C.E, and Srinivasan. A. (1995). Functional analysis of HIV-1 Vpr: Identification of determinants essential for subcellular localization. Virology 212: 331-339. 65, 204, 2003.

15. Mahalingam. S., Khan. S.A., Murali. R., Jabbar. M.A., Monken. C.E., Collman. R.G, and Srinivasan. A. (1995). Mutagenesis of the putative α-helical domain of the Vpr protein of HIV- 1: Effect on stability and virion incorporation. Proc. Natl. Acad. Sci. USA 92: 3794-3798.

Book Chapter

1. Rajendra Kumar. P., Singhal. P.K, and Mahalingam. S. (2004) A transferable signal mediates nuclear import of simian immunodeficiency virus Vpx protein. 173-178. Deep Roots, Open Skies: New Biology in India. Eds. S.K. Basu., Batra J.K and D.M. Salunke. Narosa Publishing House, New Delhi, India.

2. Srilakshmi, P., Rajendra Kumar. P and Mahalingam. S. (2007) HIV-1 pathogenesis: Role of viral protein R. 186-200. Research Issues in HIV/AIDS. Eds. D. Raghunath and C. Durga Rao.Tat McGraw-Hill Publishing company Limited, New Delhi.

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