| Padma
Priya (DOJ : Jan
2007)
Email
ID :
padmapriya@smail.com , vedanthi@gmail.com
Education : BSc
(Botany/zoology/chemistry)
Osmania University,
Msc (Zoology) Osmania University
Research
area:
Computational
Drug design,
Protein-Ligand
interactions,Bio-informatics,Anti-inflammator
drugs
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For a great many
people, debilitating
pain is a constant backdrop of daily life. And the numbers affected
are set to
increase.
As demographics
change and the mean age of the
population rises, the incidence of chronic
diseases like diabetes, cardiovascular disease,
and
rheumatoid arthritis is expected to
skyrocket, and with
it, the need
for better anti-inflammatory drugs and analgesics. With
the withdrawal
of the popular drugs in the recent times, there is a need for enhanced
understanding of
pain mechanisms which will not
only provide novel targets
for medical intervention but also provide painkillers
with
markedly improved
toxicities and side effect profiles.
The increasing knowledge of the specific
prostaglandin
synthases and
their ligands through
structure and target
based drug design
approaches will enables novel drug design strategies which
in turn will help in accelerating
and optimizing the design of novel drugs and
provide many newopportunities
for
developing novel therapeutics.
I plan to
investigate the role
of specific prostaglandin synthases with an emphasis on the enzyme
Prostaglandin E synthase and its inhibitors.
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