Developmental Genetics Lab

| Cellular Slime molds| Research overview | Publications | Lab members |


      rbaskar@iitm.ac.in

Phone   91-44-2257 4110 (office); 91-44-2257 5113 (lab)

During embryonic development, a single cell becomes a complex multicellular organism with different cell types arranged in a specific pattern. Thus, a uniform sheet of cells generates a pattern such as spots or stripes seen in the coat color of many animals. The broad interest of our lab is in understanding a specific mechanism of pattern formation called lateral inhibition during which, a cell that takes a particular identity inhibits the very adjacent cells from taking the same cell fate, thereby generating a pattern. We use the well-known model Dictyostelium to understand mechanisms of lateral inhibition.

Using Arabidopsis as a flowering plant model, we are interested in estimating the spontaneous mutations induced after hybridization. Further we are trying to ascertain if parental reproductive age affects the types/ rates of somatic mutations and meiotic recombination rates in the subsequent generation. To know more, visit the research overview section.