Developmental Genetics Lab

| Cellular Slime molds| Research overview | Publications | Lab members |


      rbaskar@iitm.ac.in

Phone   91-44-2257 4110 (office); 91-44-2257 5113 (lab)

During embryonic development, a single cell becomes a complex multicellular organism with different cell types arranged in a specific pattern. Thus, a uniform sheet of cells generates a pattern such as spots or stripes as seen in the coat color of many animals. The broad interest of our lab is in understanding a specific mechanism of pattern formation called lateral inhibition during which, a cell that takes a particular identity inhibits the very adjacent cells from taking the same cell fate, thereby generating a pattern. We use the well-known model Dictyostelium to understand mechanisms of lateral inhibition.

Using the model flowering plant Arabidopsis, we try to understand if seed storage age and parental age at reproduction could affect the somatic mutation and meiotic recombination rates in their transgenerational progenies. We use a combination of detector lines which allows the quantitation of different kinds of spontaneous mutations and meiotic recombination (MR) rates. To know more, visit the research overview section.