PUBLICATIONS

PUBLICATIONS / CONFERENCE PRESENTATIONS


2018

Puvendran K.*, K. Anupama*, G. Jayaraman (2018)
Real time monitoring of hyaluronic acid fermentation by in-situ transflectance spectroscopy, Applied Microbiology and Biotechnology (In Press; DOI: 10.1007/s00253-018-8816-9).
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2017

Doss S.S., N.P. Bhatt, G. Jayaraman (2017)
Improving the accuracy of hyaluronic acid molecular weight estimation by conventional size exclusion chromatography, Journal of Chromatography B , 1060, 255 – 261.
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2016

Kaur M., G. Jayaraman (2016)
Hyaluronan Production and Molecular Weight is Enhanced in Pathway-Engineered Strains of Lactate Dehydrogenase-Deficient Lactococcus lactis, Metabolic Engineering Communications,3, 15-23.
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Rajendran V., K. Puvendran, Bharath Raja Guru, G. Jayaraman (2016)
Design of aqueous two-phase systems for purification of hyaluronic acid produced by metabolically engineered Lactococcus lactis, Journal of Separation Science,39, 655-662.
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2015

Bera S.*, K. Thillai*, K. Sriraman, G. Jayaraman (2015)
Process strategies for enhancing recombinant streptokinase production in Lactococcus lactis cultures using P170 expression system, Biochemical Engineering Journal,93, 94-101.
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Badri, A., K. Raman, G. Jayaraman (2015)
Investigation of metabolic capabilities of recombinant lactococcus lactis for production of hyaluronic acid using constraint based genome scale models,Proceedings of 5th International Conference on Biomolecular Engineering 2015,85-87.
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2014

Hmar R.V., S.B. Prasad, G. Jayaraman*, K. B. Ramachandran* (2014)
Chromosomal integration of hyaluronic acid synthesis (has) genes enhances the molecular weight of hyaluronan produced in Lactococcus lactis, Biotechnology Journal,9,1554–1564.
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Chauhan A.*, Badle S.S.*, K.B. Ramachandran, G. Jayaraman (2014)
The P170 expression system enhances hyaluronan molecular weight and production in metabolically-engineered Lactococcus lactis,Biochemical Engineering Journal,90,73-78.
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Badle S.S., G. Jayaraman, K.B. Ramachandran (2014)
Ratio of intracellular precursors concentration and their flux influences hyaluronic acid molecular weight in Streptococcus zooepidemicus and recombinant Lactococcus lactis,Bioresource Technology,163,222-227.
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2013

Baikadi A.K., M. Kaur, S. Sreeja, G. Jayaraman, S. Narasimhan (2013)
Extraction of pure component spectrum from mixture spectra containing a known diluent, 10th IFAC Proceedings,Vol.10, 649-653.
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Kandasamy V., H. Vaidyanathan, I. Djurdjevic, E. Jayamani, K.B. Ramachandran, W. Buckel, G. Jayaraman, S. Ramalingam (2013)
Engineering Escherichia coli with acrylate pathway genes for propionic acid synthesis and its impact on mixed-acid fermentation,Applied Microbiology and Biotechnology,97(3),1191-1200.
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2012

Prasad S., K.B. Ramachandran, G. Jayaraman (2012)
Transcription analysis of hyaluronan biosynthesis genes in Streptococcus zooepidemicus and metabolically engineered Lactococcus lactis, Applied Microbiology and Biotechnology,94:1593–1607.
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2011

Vaidyanathan H., V. Kandasamy, G.G. Ramakrishnan, KB Ramachandran, G. Jayaraman, S. Ramalingam (2011)
Glycerol conversion to 1,3 - Propanediol is enhanced by the expression of a heterologous alcohol dehydrogenase gene in Lactobacillus reuteri, AMB Express,1:37.
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Jain G., G. Jayaraman, O. Kokpinar, U. Rinas, B. Hitzmann (2011)
On-line monitoring of recombinant bacterial cultures using multi-wavelength fluorescent spectroscopy,Biochemical Engineering Journal,58-59,133-139.
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Palani S., L. Gueorguieva, U. Rinas, A. Seidel-Morgenstern, G. Jayaraman (2011)
Recombinant protein purification using gradient-assisted simulated moving bed hydrophobic interaction chromatography. Part I:Selection of chromatographic system and estimation of adsorption isotherms, Journal of Chromatography A,1218,6396-6401.
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Gueorguieva L., S. Palani, U. Rinas, G. Jayaraman, A. Seidel-Morgenstern, (2011)
Recombinant protein purification using gradient-assisted simulated moving bed hydrophobic interaction chromatography. Part II: Process design and experimental validation,,Journal of Chromatography A,1218,6402-6411.
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2010

Prasad S., G. Jayaraman, K.B. Ramachandran (2010)
Hyaluronic acid production is enhanced by the additional coexpression of UDP-glucose Pyrophosphorylase in Lactococcus lactis, , Applied Microbiology and Biotechnology,86, 273-283.
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2009

Palani S., G. Jayaraman, L. Gueorguieva, U. Rinas, A. Seidel-Morgenstern (2009)
Kontinuierliche Aufreinigung der rekombinanten Streptokinasemittels Simulated Moving Bed (SMB)-Chromatographie, Chemie Ingenieur Technik,81(8),P11.35, 1291.
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Jain G., B. Hitzmann, U. Rinas, G. Jayaraman (2009)
2D-Fluoreszenzspektroskopie zur Stressanalyse bei der rekombinanten Proteinproduktion,Chemie Ingenieur Technik,81(8),P11.37,1292.
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2008

Balagurunathan, B. and G. Jayaraman (2008)
Theoretical and experimental investigation of chaperone effects on soluble recombinant proteins in Escherichia coli: Effect of free DnaK level on temperature-induced recombinant streptokinase production, Systems and Synthetic Biology,2,27-48.
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Sriraman, K. and G. Jayaraman (2008)
HtrA is essential for efficient secretion of recombinant proteins by Lactococcus lactis,Applied and Enviromental Microbiology,74(23),7442-7446.
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Balagurunathan, B. and G. Jayaraman (2008)
Cellular response to accumulation of recombinant proteins in the E. coli inner membrane: Implications for proteolysis and productivity of the secretory expression system, Biochemical Engineering Journal,39,74-83.
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Balagurunathan, B., N.S. Ramchandra, G. Jayaraman (2008)
Enhancement of stability of recombinant streptokinase by intracellular expression and single step purification by hydrophobic interaction chromatography,Biochemical Engineering Journal,39(1),84-90.
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2007

Ramalingam, S., P. Gautam, K.J. Mukherjee, G. Jayaraman (2007)
Effects of post-induction feed strategies on secretory production of recombinant streptokinase in Escherichia coli, Biochemical Engineering Journal,33(1),34-41.
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Balagurunathan, B. and G. Jayaraman (2007)
Dynamics of cellular response to recombinant protein overexpression in Escherichia coli, in G. Subramanian (Ed.),Bioseparation and Bioprocessing: A Handbook (2nd Ed., Wiley VCH),Vol.1,101-122.
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2006

Sriraman, K. and G. Jayaraman (2006)
Enhancement of recombinant streptokinase production in Lactococcus lactis by suppression of acid tolerance response, Applied Microbiology and Biotechnology,72(6),1202–1209.
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2005

B. Balagurunathan, G. Jayaraman (2005)
Kinetic analysis of the envelope stress response during the temperature induced periplasmic expression of recombinant streptokinase in escherichia coli, AIChE Annual Meeting 2005, Conference Proceedings,6297-6298.
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Velu, M., B. Balagurunathan, G. Jayaraman (2005)
Online performance monitoring of recombinant protein production in a fed-batch bioreactor,AIChE Annual Meeting 2005, Conference Proceedings,8445.
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2003

Balagurunathan, B. and G. Jayaraman (2003)
Modeling of cellular stress response to recombinant protein production in bacterial systems, Proceedings of the Indian Chemical Engineering Congress 2003.
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1998

Vellanki, P., I. Marison, G. Jayaraman and K. Jayaraman (1998)
Calorimetric optimisation of growth and sporulation of Bacillus thuringiensis var galleriae, Thermochimica Acta309,105 – 110.
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1997

Cramer, S.M., J. Moore, A. Kundu, Y-F Li and G. Jayaraman (1997)
Displacement chromatography of proteins using low molecular weight displacers, Biotechnology Advances,15(1),145.
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Cramer, S.M., J. Moore, A. Kundu, Y-F Li and G. Jayaraman (1997)
Displacement chromatography of proteins using low molecular weight anionic displacers,Biotechnology Advances,15(3-4),749.
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1995

Kundu, A., S. Vunnum, G. Jayaraman and S.M. Cramer (1995)
Protected amino acids as novel low-molecular-weight displacers in cation-exchange displacement chromatography,Biotechnology and Bioengineering,48,452-460.
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Jayaraman, G. Y-F Li, J A. Moore and S M. Cramer (1995)
Ion-Exchange Displacement Chromatography of Proteins: Dendritic Polymers as Novel Displacers,Journal of Chromatography A,702 (1-2), 143-156.
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1993

Cramer, S.M. and G. Jayaraman (1993)
Preparative Chromatography in Biotechnology,Current Opinion in Biotechnology,4(2),217 – 225.
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Jayaraman, G., S.D. Gadam and S.M. Cramer (1993)
Ion-Exchange Displacement Chromatography of Proteins:Dextran Based Polyelectrolytes as High Affinity Displacers,Journal of Chromatography A,630,53 – 68.
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Gadam, S.D., G. Jayaraman and S.M. Cramer (1993)
Characterization of Non-Linear Adsorption Properties of Dextran Based Polyelectrolyte Displacers in Ion - Exchange Systems,Journal of Chromatography A,630,37-52.
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Subramanian, G., M. W. Phillips, G. Jayaraman and S. M. Cramer (1989)
Displacement Chromatography of Biomolecules in Large Particle Diameter Systems,Journal of Chromatography A,484, 225 – 236.
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