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Murugan R

murugan-r
Assistant Professor
Ph.D, Tata Institute of Fundamental Research
M.Sc, Tamil Nadu Agriculture University
Office: BT 506
Tel: +91-44-2257-4116
Email: rmurugan@iitm·ac·in
Lab: BT 516 (Website)

Research Interests

Random walks and jumps in Biology
Kinetics of DNA-protein & DNA-DNA interactions
Biochemical & Genetic Networks – Systems Biology

Publications

  1. Murugan R. Directional dependent dynamics of protein molecules on DNA Physical review. E, Statistical, nonlinear, and soft matter physics 79, 041913 (2009)
  2. Murugan R. Multiple Stochastic Point Processes in Gene Expression J Stat Phys 131 (1) , 153 – 165 (2008) (Epub 25 Jan 2008) doi: 10.1007/s10955-008-9484-4
  3. Murugan R. Generalized theory of site-specific DNA-protein interactions. Physical review. E, Statistical, nonlinear, and soft matter physics 76 (1 Pt 1) , 011901 (2007) (Epub 02 Jul 2007) PubMed ID:(17677488)
  4. Murugan R. Action at distance along the DNA: a random jump model on enhancer action. Journal of theoretical biology 248 (4) , 696-705 (2007) (Epub 09 Jun 2007) PubMed ID:(17673258)
  5. Murugan R. Effect of external fluctuations on the affinity-specificity negative correlation in DNA-probe interactions. Physical review. E, Statistical, nonlinear, and soft matter physics 73 (5 Pt 1) , 051915 (2006) (Epub 23 May 2006) PubMed ID:(16802975)
  6. Murugan R. Critical jump sizes in DNA-protein interactions. Biophysical chemistry 120 (2) , 143-7 (2006) (Epub 01 Dec 2005) PubMed ID:(16324783)
  7. Murugan R. Stochastic transcription initiation: Time dependent transcription rates. Biophysical chemistry 121 (1) , 51-6 (2006) (Epub 27 Jan 2006) PubMed ID:(16442697)
  8. Murugan R. Mean first passage time calculation for a one-dimensional random walk with random absorbing boundary J. Phys. A: Math. Gen. 39 (13) , L199 – L205 (2006) (Epub 15 Mar 2006) doi: 10.1088/0305-4470/39/13/L01
  9. Murugan R. Mean first passage time calculation for the random walk with random step size J. Phys. A: Math. Gen. 39 (7) , 1575 – 1580 (2006) (Epub 01 Feb 2006) doi: 10.1088/0305-4470/39/7/004
  10. R. Murugan. On the origin of affinity-specificity negative correlation in DNA- probe interactions, Biophys. Chem., 116, 105-9 (2005).
  11. Murugan R. DNA-protein interactions under random jump conditions. Physical review. E, Statistical, nonlinear, and soft matter physics 69 (1 Pt 1) , 011911 (2004) (Epub 29 Jan 2004) PubMed ID:(14995651)
  12. Murugan R. Competitive model on denaturant-mediated protein unfolding. Biophysical journal 84 (2 Pt 1) , 770-4 (2003) PubMed ID:(12547761 )
  13. Murugan R. A theory on the origin of cooperativity in DNA renaturation kinetics. Biophysical chemistry 106 (2) , 173-8 (2003) PubMed ID:(14556905)
  14. Murugan R. A stochastic model on DNA renaturation kinetics. Biophysical chemistry 104 (3) , 535-41 (2003) PubMed ID:(12914901)
  15. Murugan R. Revised theory on DNA renaturation kinetics and its experimental verification. Biochemical and Biophysical Research Communications 293 (2) , 870-3 (2002) PubMed ID:(12054552)
  16. Murugan R. Sample size autocorrelation analysis of kinetic data: Resolving reaction path heterogeneity J. Chem. Phys. 117 (13) (2002) doi: 10.1063/1.1503335
  17. Murugan R. Solution to Michaelis–Menten enzyme kinetic equation via undetermined gauge functions: Resolving the nonlinearity of Lineweaver–Burk plot J. Chem. Phys. 117 (9) (2002) doi: 10.1063/1.1496459