Our laboratory aims to identify genes that regulate germ cell development. We investigate this process in the C. elegans model with a particular focus on the role of RNA-binding proteins and their targets that regulate germ cell development.
Revathi K, Subramaniam K. (2022). "An efficient negative selection marker for Mos1 -mediated single-copy integration in Caenorhabditis elegans", MicroPublication Biology, DOI: doi: 10.17912/micropub.biology.000647.
Kumar GA, Subramaniam K. (2018). "PUF-8 facilitates homologous chromosome pairing by promoting proteasome activity during meiotic entry in C. elegans", Development, 145, DOI: doi: 10.1242/dev.163949.
Pushpa K, Kumar GA, Subramaniam K. (2013). "PUF-8 and TCER-1 are essential for normal levels of multiple mRNAs in the C. elegans germline", Development, 140, pp. 1312-1320, DOI: doi: 10.1242/dev.087833.
Vaid S, Ariz M, Chaturbedi A, Kumar GA, Subramaniam K. (2013). "PUF-8 negatively regulates RAS/MAPK signalling to promote differentiation of C. elegans germ cells", Development, 140, pp. 1645-1654, DOI: doi: 10.1242/dev.088013.
Maheshwari R, Pushpa K, Subramaniam K. (2016). "A role for post-transcriptional control of endoplasmic reticulum dynamics and function in C. elegans germline stem cell maintenance", Development, 143, pp. 3097-3108, DOI: doi: 10.1242/dev.134056.
Vishnupriya, R., Thomas, L., Wahba, L., Fire, A., Subramaniam, K.
(2020). "PLP-1 is essential for germ cell development and germline gene silencing in Caenorhabditis elegans", Development (Cambridge), 147(22), pp. dev195578, DOI: 10.1242/dev.195578.
Buvani, A.P.E., Subramaniam, K. (2023). "The C. elegans gene gvd-1 promotes late larval development and germ cell proliferation", Biology Open , 12(7), pp. bio059978, DOI: 10.1242/bio.059978.
