Home » Faculty » Rama S Verma

Rama S Verma

Ph.D., Jawaharlal Nehru University
M.Phil, Jawaharlal Nehru University
Office: BT 201
Tel: +91-44-2257-4109
Email: vermars@iitm·ac·in
Lab: BT 213 (Website)

Research Interests

1- Stem cell proliferation related studies

  • A- Role of Osteoblasts in Stem Cell Proliferation
    Hematopoiesis is an exquisitely regulated physiological process, which results in the appropriate production of blood cells throughout life. Over the past four decades our understanding of the cellular and molecular basis of hematopoietic regulation has become quite sophisticated. Several hematopoietic growth factor polypeptide hormones have been identified through molecular cloning, which play a key role in this process. In many respect, our current dynamic model of hematopoietic is the leading paradigm in molecular histology. It has established a framework to apply to cell differentiation and renewal in diverse tissue, including liver, skin and intestinal epithelium. Despite these advances, the most important details of the cellular and molecular regulation of stem cell self- renewal and differentiation remain elusive. We are currently addressing these issues through the following:
  1. Role of permissive and inductive microenvironment in bone marrow in context to proliferation of stem cell
  2. Role of osteoblast in the proliferation of stem cell
  • B- Stem Cell and its Regenerative Potential

2- Construction of Novel & New fusion Toxin (Immunotoxins)

Recombinant immunotoxins are antibody-toxin chimeric molecules that kill cancer cells via binding to a surface antigen, internalization and delivery of the toxin moiety to the cell cytosol. In the cytosol, toxins catalytically inhibit a critical cell function and cause cell death. The antibody portion of the chimera targets antigens that are expressed preferentially on the surface of cancer cells. Truncated versions of either diphtheria toxin (DT) or Pseudomonas exotoxin (PE) can be used to construct fusions with cDNAs encoding antibody fragments or cell- binding ligands. Presently, in our lab we have designed several novel constrct which are truncated version of known immunotoxins and novel humanized toxin utilizing the pre-apoptoctic segment of human origin to combat the problems associates with the immnogenicity of the toxin fragment and the non-targeted toxicity noted while treating certain cancers.

3- Cloning & Expression of Therapeutic Protein that have Clinical Importance

4- Development of MAB against EpCAM for Targeting Retinoblastoma with Nanoparticle

5- Biochemical and Molecular Characterization of membrane Protein Receptor) Presently our interest is in “Identification and Purification of Methotrexate Binding protein from the T Lymphocytes

6- Nanotechnology Using synthetic biodegradable micro-molecules and biodegradable biopolymer as scaffold for stem cell differentiation into cardiac tissue for heart injury repair.



(A) International refereed journals (starting from recent)


  1. Raj Pranap Arun, Divya Sivanesan, Prasanna Vidyasekar, Rama Shanker Verma (2017) TEN/FOXO3/AKT pathway regulates cell death and mediates morphogenetic differentiation of Colorectal Cancer Cells under Simulated Microgravity Scientific Report (accepted)DOI:10.1038/s41598-017-06416-4
  2. Antara Banerjee, Surajit Pathak, Vimala Devi S, Dharani Vasan, Ramachandran Murugesan and Rama S Verma (2017) Strategies for targeted drug delivery in treatment of colon cancer – current trends and future perspectives Drug Discovery Today (10.1016/j.drudis.2017.05.006)
  3. Swati Choudhary, Stefan Barth, Rama S Verma (2017) SNAP tag technology: a promising tool for ex vivo immunophenotyping”, Molecular Diagnosis & Therapy. (doi: 10.1007/s40291-017-0263-2)
  4. Madumathi J., Sridevi S and Rama S Verma (2017)CD25 targeted therapy of chemotherapy resistant leukemic stem cells using DR5 specific TRAIL peptide Stem Cell Research DOI:10.1016/j.scr.2017.01.001
  5. S Jahnavi, U Saravananb, N Arthia, G S Bhuvaneshwarc, T V Kumaryd, S Rajane, R S Verma(2017) Biological and mechanical evaluation of a Bio-Hybrid scaffold for autologous valve tissue engineering Materials Science and Engineering: C Vol 73 (1), 59–71 org/10.1016/j.msec.2016.11.116
  6. Priyamvada H , Akila M , Raj Kamal Singh, Ravikrishna R, Verma R.S., Ligy Philip, Rahul Marathe, Sudheer K.P. and Gunthe S. S.(2017) Terrestrial macro fungal diversity from the tropical dry evergreen biome of southern India and its potential role in aerobiology PLOS ONE , 1-21
  7. Pavithra Shyamsunder, Milan Esner, Maunish Barvalia, Yu Jun Wu, Tomáš Loja, Huat Bay Boon, Matilde E. Lleonart, Rama S Verma, Lumir Krejci, and Alex Lyakhovich (2016) ROS-mediated defective mitophagy in Fanconi anemia is dependent on mitochondrial fission Oncotarget Aug 9. doi: 10.18632/oncotarget.11161 IF 6.4
  8. Rama S. Verma (2016) Breaking dogma for future therapy using stem cell – Where we have reached? Indian J Med Res 143, February 2016, pp 125-25
  9. Madhumathi J, Sridevi S and Rama S Verma (2016) Novel TNF-related apoptotic inducing ligand based immunotoxin for therapeutic targeting of CD25 positive leukemia Targeted Oncology 11(4), 535-547 IF 4.00
  10. Dilip bishi, Santosh Mathapati, Jayarama R. Venugopal, Soma Guhathakurta, Kotturathu M. Cherian, Rama S. Verma and Seeram Ramakrishna(2016) A Patient-inspired Ex Vivo Liver Tissue Engineering Approach with Autologous Mesenchymal Stem Cells and Hepatogenic Serum Advanced Healthcare Materials5 (9) 1058–1070 IF 5.8
  11. Swati Choudhary, Alessa Pardo, Reinhard Rosinke, Janendra K Batra, Stefan Barth andRama S Verma (2016) Targeting c-kit receptor in neuroblastomas and colorectal cancers using Stem Cell Factor (SCF)-based recombinant bacterial toxins Applied Microbiology and Biotechnology Jan;100(1):263-77IF 3.81
  12. Prasanna Vidyasekar, Pavithra Shyamsunder, Sanjeeb Kumar Sahoo and Rama Shanker Verma (2016) Scaffold free and scaffold assisted 3-Dimensional culture enhances differentiation of bone marrow stromal cells,” In Vitro Cellular & Developmental Biology – Animal. Feb;52(2):204-17, PMID: 26542170
  13. Jincy Joy, Amlan Gupta, Sarvepalli Jahnavi, Rama S Verma, Alok R Ray and Bhuvanesh Gupta,(2016) Understanding the in situ cross linked gelatin hydrogel Polymer International 65 (2),181–191: IF 2.
  14. Morphological characteristics of bioaerosols from contrasting locations in southern tropical India – A case study (2015) Aswathy E. Valsan, Hema Priyamvada, R. Ravikrishna, Viviane R. Despres, C.V. Biju, Lokesh K. Sahu, Ashwini Kumar, R.S. Verma, L. Philip, Sachin S. Gunthe Atmospheric Environment 122, 321–331 IF 3.28
  15. Sugapriya Dhanasekaran, Devilakshmi Sithambaram, Kavitha Govarthananan, Bijesh Biswal and Rama Verma (2015) An Efficient Protocol for Deriving Liver Stem Cells from Neonatal Mice: validating its Differentiation potential. Analytical Cellular Pathology Volume 2015:219206,
  16. Abhalaxmi Singh, Sumeet Jain, Shantibhusan Senapati, Rama Shanker Vermaand Sanjeeb K. Sahoo (2015) Magnetic Nanoparticles Labeled Mesenchymal Stem Cells: A Pragmatic Solution toward Targeted Cancer Theranostics Advanced Healthcare Materials DOI:1002/adhm.201500343IF 5.8
  17. Prasanna Vidyasekar, Pavithra Shyamsunder, Rajpranap Arun,Rajalakshmi Santhakumar, Nand Kishore Kapadia, Ravi Kumar, RamaShanker Verma (2015) Genome Wide Expression Profiling of Cancer Cell Lines Cultured in Microgravity Reveals Significant Dysregulation of Cell Cycle and MicroRNA Gene Networks PLOS ONEAug 21;10(8):e0135958, DOI:10.1371/journal.pone.0135958 IF 3.73
  18. Prasanna Vidyasekar, Pavithra Shyamsunder, Rajalakshmi Santhakumar, Rajpranap Arun, Rama Shanker Verma (2015) A simplified protocol for the isolation and culture of cardiomyocytes and progenitor cells from neonatal mouse ventricles European Journal of Cell Biology94(10):444-52: IF 3.82
  19. Madhumathi J, Devilakshmi S. and Verma R. S.(2015) Immunotoxin therapy for hematologic malignancies: where are we heading? Drug Discovery Today Feb; 21(2):325-32.IF 5.96
  20. Jahnavi S., Kumary T.V., Bhuvaneshwar G.S., Natarajan T.S., and Verma R. S. (2015) Engineering of a polymer layered bio-hybrid heart valve scaffold. Materials Science and Engineering C51:263-73IF2.7
  21. Parameswaran S, Santhakumar R, Vidyasekar P, Verma RS (2015)Enrichment of cardiomyocytes in primary cultures of murine neonatal hearts.Methods Mol Biol 1299:17-2
  22. Pavithra Shyamsunder, Rama S. Verma, and Alex Lyakhovich (2015) ROMO1 regulates Redox states and serves as an inducer of NF-kappa B-driven EMT factors in Fanconi anemia Cancer letters361(1):33-8.IF 5.01
  23. 23. Rajalakshmi Santhakumar, Prasanna Vidyasekar, Rama Shanker Verma (2014)Cardiogel: A Nano-Matrix Scaffold with    Potential Application in Cardiac Regeneration  Using Mesenchymal Stem Cells PLoS ONE 9(12): e114697.doi:10.1371/journal.pone.0114697 IF 3.73
  24. 24. Viswambari Devi R., Doble M., and Verma S Rama (2015) Nanomaterials for early detection of cancer biomarker with special emphasis on gold nanoparticles in immunoassays/sensors. Biosensors and Bioelectronics Jan 29;68C:688-698IF 6.
  25. 25. Alex Epanchintsev, Pavithra Shyamsunder, Rama S. Verma, andnAlex Lyakhovich (2014) IL-6, IL-8, MMP-2, MMP-9 are overexpressed in Fanconi Anemia Cells through a NF-kB/TNF-a Dependent Mechanism Molecular Carcinogenesis DOI 10.1002/mc.22240 IF 4.77
  26. Giovanni Pagano, Pavithra Shyamsunder, Rama S. Verma, Alex Lyakhovich. Damaged mitochondria in Fanconi anemia – an isolated event or a general phenomenon? Oncoscience. 2014;1:287-295.
  27. Dillip Kumar Bishi, Santosh Mathapati, Kotturathu Mammen Cherian, Soma Guhathakurta and Rama Shanker Verma (2014) In Vitro Hepatic Trans-Differentiation of HumanMesenchymal Stem Cells Using Sera from Congestive/Ischemic Liver during Cardiac Failure Plos One: March 18, 2014, DOI: 10.1371/journal.pone.0092397 IFJahnavi S, Arthi N, Pallavi S, Selvaraju C, Bhuvaneshwar G S, Kumary T V, Rama Verma(2017) Nanosecond Laser Ablation Enhances Cellular Infiltration in a Hybrid Tissue Scaffold Materials Science & Engineering C 77 190–201.
  28. Pavithra Shyamsunder, Kripa S Ganesh, Prasanna Vidyasekar, Sheila Mohan and Rama Shanker Verma (2013) “Identification of Novel target Genes involved in Indian Fanconi Anemia patients using microarray” Dec 1;531(2):444-50 10.1016/j.gene.2013.08.082 IF
  29. Sreejit Parameswaran, Sujeet Kumar, Rama Shanker Verma, Rajendra K Sharma ( 2013) “Cardiomyocyte culture – an update on the in vitro cardiovascular model and future challenges” Canadian Journal of Physiology and Pharmacology (doi: 10.1139/cjpp-2013-0161) IF
  30. Pavithra Shyamsunder, Prasanna Vidyasekar, Akshay Ranjan Shukla, Sheila Mohan, and Rama Shanker Verma (2013) Lowered Expression Levels of a Tumor Supresser Gene- Caveolin-1 Within Dysregulated Gene Networks of Fanconi Anemia Sep 25;527(2) 521–528 Impact Factor 2.19
  31. Dillip Kumar Bishi, Santosh Mathapati, Jayarama Reddy Venugopal, Soma Guhathakurta, Kotturathu Mammen Cherian, Rama Shanker Verma, Seeram Ramakrishna (2013) Trans-differentiation of Human Mesenchymal Stem Cells Generates Functional Hepatospheres on Poly (L-lactic acid)-co-poly(ε-caprolactone)/collagen Nanofibrous Scaffolds Journal of Materials Chemistry B 32: 3871 4034 Impact factor 5.96
  32. Sreejit P and Verma, Rama Shanker (2013) Enhanced Cardiomyogenic Lineage Differentiation of Adult Bone Marrow Derived Stem Cells grown on Cardiogel Cell and Tissue Research Sep;353(3):443-56. DOI: 10.1007/s00441-013-1661-3 Impact Factor 3.67 Citation 1
  33. Sugapriya Dhanasekaran, Bijesh Biswal, Venil Sumantran and Rama S Verma (2013) Augmented Sensitivity to Methotrexate by Curcumin induced overexpression of Folate Receptor in KG-1 Cells Biochimie 95(8): 1567-73. Impact factor 3.02 Citation 2
  34. Mathapati S, Bishi DK, Guhathakurta S, Cherian KM, Venugopal J, Ramakrishna S, Verma RS. Nanofibers-coated acellular tissue-engineered bovine pericardium supports differentiation of mesenchymal stem cells into endothelial cells for tissue engineering. Nanomedicine 9(5):623-34 Impact factor 5.26
  35. Mrudula Mathew, Zaineb K. C., Rama Shanker Verma (2013) GM-CSF-DFF40: A Novel Humanized Immunotoxin Induces Apoptosis in Acute Myeloid Leukemia cells Apoptosis 18 (7); Impact Factor 4.77 Citation 2
  36. Sreejit P & R. S. Verma (2013) Natural ECM as Biomaterial for Scaffold Based CardiacRegeneration Using Adult Bone Marrow Derived Stem Cells Stem Cell Rev and Rep 9(2); 158-71 Impact Factor 3.74 Citation 6
  37. Santosh Mathapati, Dillip Kumar Bishi1, Soma Guhathakurta, Kotturathu Mammen Cherian, Jayarama Reddy Venugopal, Seeram Ramakrishna, Rama Shanker Verma (2012) Biomimetic acellular detoxified glutaraldehyde cross-linked bovine pericardium for tissue engineering
Materials Science and Engineering Materials for Biological Applications 33; 1561-1572, Impact Factor 2.68 Citation 2
  38. Muthumanickam Andiyappan, Subramanian Sundaramoorthy, Prasanna Vidyasekar , Natarajan Tirupattur Srinivasan and Rama Shanker Verma (2012) Characterization of electrospun fibrous scaffold produced from Indian eri silk fibroin International Journal of Materials Research 5; 498-506 Citation 1
  39. Sreejit P, Bishi, Dillip K and Verma Rama S (2012) Generation of mesenchymal stem cell lines from murine bone marrow Cell and Tissue Research 350(1), 55-68. Impact Factor 3.67 Citation 5
  40. Madhumathi J and Verma R S (2012) Therapeutic Targets and Recent Advances in Protein Immunotoxins Current opinion in Microbiology 15, 300–309 Impact Factor 7.92 citation 32
  41. Sandip Madhusudan Swain, Sreejit Parameswaran, Giriraj Sahu, Rama Shanker Verma and Amal Kanti Bera (2012) Proton-gated ion channels in mouse bone marrow stromal cells Stem Cell Research 9, 59–68 Impact Factor 5.12 Citation 3
  42. Anjana, D., K. Anitha Nair, N. Somashekara, M. Venkata, R. Sripathy, Rajesh Yelucheri, H. Parmar, R. Upadhyay, S. Rama Verma and C.N. Ramchand (2012) Development of Curcumin Based Ophthalmic Formulation American Journal of Infectious Diseases 8 (1): 41-49
  43. Venkata, M., R. Sripathy, D. Anjana, N. Somashekara, A. Krishnaraju, S. Krishanu, M. Murali, S. Rama Verma and C.N. Ramchand (2012) In Silico, In Vitro and In Vivo Assessment of Safety and Anti-inflammatory Activity of Curcumin American Journal of Infectious Diseases 8 (1): 26-33
  44. Moutushy Mitra, Mallikarjuna Kandalam, Anju Harilal, Rama Shenkar Verma, Uma Maheswari, S. Swaminathan, Subramanian Krishnakumar (2012) EpCAM is a putative stem marker in retinoblastoma and an effective target for T-cell-mediated immunotherapy Molecular Vision 17; Impact Factor 2.54 Citation: 9
  45. Chandana Tekkatte, Prasanna Vidyasekar, Nand Kishore Kapadia and Rama S Verma (2012) “Enhancement of adipogenic and osteogenic 1 differentiation of human bone marrow derived mesenchymal stem cells with umbilical cord blood serum supplementation Cell and Tissue Research 347(2) 383-395 Impact Factor 3.11 Citation 9
  46. Sithanbaram Devilakshmi, Palanivelu Shanthi, subramanian Krishnakumar Sahoo Sanjeeb and Verma Rama S (2011) “Monoclonal Antibody for Specific Targeting of Ep-CAM in Various Carcinomas” Hybridoma Volume 30, Number 6, 511-518 Impact Factor 0.462 Citation 2
  47. Sreejit P and Verma R. S. (2011) Scanning Electron Microscopy Preparation Protocol For Differentiated Stem Cells Analytical Biochemistry 15; 416 (2): 186-90 Impact Factor 3.256 citation: 7
  48. Swati Choudhary, Mrudula Mathew and Rama S. Verma (2011) “Therapeutic potential of anticancer immunotoxins” Drug Discovery Today (2011), 16 (11/12), 495-503 Impact Factor: 7.25 Citation: 38
  49. Mitra Moutushy, Kandalam Mallikarjuna, Sundaram, C, Verma Rama, Maheswari Uma, Swaminathan S, Subramanian Krishnakumar (2011)”Reversal of stathmin mediated microtubule destabilization sensitizes retinoblastoma cells to low dose of anti microtubule agents: A novel synergistic therapeutic intervention Invest Ophthalmol Vis Jul 23; 52(8): 5441-8. Impact Factor 3.56 Citation: 11
  50. Sreejit P and R S Verma (2011) “Cardiogel supports adhesion, proliferation and differentiation of stem cells with increased oxidative stress protection” Europian Cell and Material Jourrnal (eCM) 21: 107 – 121 Impact Factor 9.36 Citation: 3
  51. Santosh Mathapati, Rama Shanker Verma, Kotturathu Mammen Cheriana and Soma Guhathakurta (2011) Inflammatory responses of tissue-engineered xenografts in a clinical Scenario Interactive Cardio Vascular and Thoracic Surgery 12:360-365 Impact Factor 2.19 citation 5
  52. Potala Sirisha and Verma Rama S (2011) Targeting head and neck squamous cell carcinoma using a novel fusion toxin-diphtheria toxin/HN-1. Molecular Biology Report 38(2): 1389-97. Impact Factor: 2.92 citation: 2
  53. Potala Sirisha and Verma Rama S (2010) Modified DT-IL2 fusion toxin targeting uniquely IL2R alpha expressing leukemia cell lines-Construction and characterization. Journal of Biotechnology 148,147-155 Impact Factor: 3.22 Citation: 4
  54. Moutushy Mitra, Fahima Dilnawaz, Ranjita Misra, Anju Harilal, Rama Shanker Verma, Sanjeeb K. Sahoo and Subramanian Krishnakumar (2010) Toxicogenomics of nanoparticulate delivery of etoposide: potential impact on nanotechnology in retinoblastoma therapy Cancer Nanotechnology 2,1-6 Citation 3
  55. Santosh Mathapati, Satish Galla, Rama Shanker Verma, Kotturathu Mammen Cherian, Soma Guhathakurta (2010) Qualitative and Quantitative Detection of Sodium Deoxycholic Acid in Decellularized Tissue. Ind J of Thoracic Cardiovascular Surgery (2010) 26:129–131 citation 2
  56. Moutushy Mitra, Mallikarjuna Kandalam, Rama Shanker Verma, Uma Maheswari and Subramanian Krishnakumar (2010) Genome wide Changes accompanying the knockdown of EpCAM in retinoblastoma. Molecular vision 16: 828-84. Impact Factor: 2.54: Citation: 12
  57. Sirisha Potala and Rama S Verma (2010) A novel fusion protein Diphtheria Toxin-Stem Cell Factor (DT-SCF) – purification and characterization. Applied Biochemistry and Biotechnology 162(5): 1258-69 Impact Factor: 1.87: Citation: 2
  58. Bijesh K Biswal, Niladri B. Debata and Rama S Verma (2010) Development of a targeted siRNA delivery system using FOL-PEG-PEI conjugate”. Molecular Biology Reports 37 (6) 2919-2926 Impact Factor: 2.92: Citation: 19
  59. Pavithra P. S. Jannani S., Charumathi R., Indumathi J., and Verma Rama S. (2010) “Antibacterial activity of Plants Used in Indian Herbal Medicine. International Journal of Green Pharmacy 4 (1), 22-29: Citation: 31
  60. Santosh Mathapati, Sarasa Bharati Arumugam, Rama Shanker Verma (2010) “High cholesterol diet increases MMP9 and CD40 immunopositivity in early atherosclerotic plaquein rabbits”. Acta histochimica, 112, 618-623 Impact Factor: 1.82 Citation: 8
  61. Sunnel R, Dillip K Bishi, Rama S Verma, Kothurattu M Cherian and Soma Guhathakurta (2009) A multiplex PCR for characterization of human mesenchymal stem cells. Biotechnology Letter 31(12): 1843-50. Impact Factor: 1.68: Citation 9
  62. Pavithra S, N.Sreevidya, Rama S Verma (2009) Antibacterial and antioxidant activity of methanol extract of Evolvulus nummularius (L). Indian Journal of pharmacology vol. 41(5) 233-236 Citation: 12
  63. Bijesh K Biswal, K. Manniledam, Rama S Verma and E.Prasad (2009) Tumor Cell Imaging Using the Intrinsic Emission from PAMAM Dendrimer: A Case Study with HeLa Cells. Cytotechnology 61(1-2): 17-24: Impact Factor: 1.75: Citation: 6
  64. Bijesh K Biswal and Rama S Verma (2009) “Differential Usage of the Transport Systems for Folic acid and Methotrexate in Normal Human T-Lymphocytes and Leukemic Cells”. The Journal of Biochemistry 146 (5), 693–703 Impact Factor: 2.14 Citation: 8
  65. Chandana Mohanty, Geetanjali Arya, Rama S Verma and Sanjeeb K Sahoo (2009) Nanobiotechnology: Application of Nanotechnology in Therapeutics and Diagnosis Journal of Nano biotechnology: biomedicine 1(1), B24 – B38. Citation: 2
  66. Mrudula Mathew and Rama S. Verma (2009) Humanized Immunotoxins – A New Generation of Immunotoxins Cancer Sciences 100, (8), 1359-1365: Impact factor: 3.47: Citation: 81
  67. Pavithra P S., Sreevidya N. and Rama S Verma (2009) Antibacterial activity and chemical composition of essential oil of Pamburus missionis Journal of Ethanopharmacology 124(1) 151-153: Impact Factor: 3.01: Citation: 16
  68. Pavithra P S., Sreevidya N. and Rama S Verma (2009) A review of chemistry and biological activity of genus Atalantia (Rutaceae) Journal of Medicinal and Aromatic Plant Science 31, 63-72. Impact Factor: 2.26: Citation: 1
  69. M. Himabindu, D. Sugapriya Muthamilselvan, Dillip Kumar Bishi, and Rama S Verma (2009) Molecular Analysis of Coagulase Gene Polymorphism in Clinical Isolates of Methicilin Resistant Staphylococcus Aureus By Restriction Fragment Lenth Polymorphism Based Genotyping American Journal of Infectious diseases 5(2): 170-176 Citation 19
  70. Pavithra P.S, Sreevidya N and Rama S Verma (2009) Antibacterial and antioxidant activity of methanol extract of Evolvulus nummularius (L). Indian Journal of pharmacology vol. 41(5) 233-236 Citation: 12
  71. Dillip kumer Bishi, Ilu Vargheese and Rama S. Verma (2008) “Molecular typing of colonizing Streptococcus agalactiae strains by Enterobacterial Repetitive Intergenic Consensus PCR (ERIC-PCR) in a Chennai based hospital” Indian journal of Microbiology 48: 291-296. Impact Factor: 0.9 Citation: 1
  72. Sirisha potala, Sanjeeb Sahoo and Rama S. Verma (2008) “Targeted therapy of cancer using Diphtheria toxin derived immunotoxins” Drug discovery Today Review 13, 17/18,807-815. Impact Factor: 7.7: Citation: 40
  73. Rallapalli S, S Verghese and Verma R S (2008) Validation of Multiplex PCR strategy for simultaneous detection and Identification of methicillin resistance staphylococcus Aureus Indian Journal on Medical Microbiology 26 (4) 360-363 Impact Factor: 1.006 Citation: 7
  74. Sreejit P., Suresh Kumar and Rama S. Verma (2008) An Improved Protocol for Primary Culture of Cardiomyocytes from Neonatal Mice In-Vitro Cellular and Developmental Biology – Animal 44, 45-50. Impact Factor: 1.312: Citation: 39
  75. Kalidoss Ramamoorthy, Sirisha Potala, and Rama S. Verma (2008) Convergence pattern studies of folate receptor Boinformation 3 (4): 168-172 (2008).
  76. Kalidoss Ramamoorthy, Sirisha Potala, and Rama S. Verma (2007) In silico analysis of functionally important residues in folate receptors. Bionformation 2 (4), 157-162
  77. Taichman R. S., Reilly M. J., Verma R. S., Ehrenman K. and Emerson S. G (2001) Hepatocyte Growth Factor is Secreted by Osteoblast and Cooperatively Permits tge survials of Haematopoietic Progenators British Journal of Haematology 112(2) 438-448. Impact Factor: 4.47 Citation: 69
  78. Verma R.S., Gianolla D., Schomichik W., and Emerson S. G (1998) Increased efficiency of liposime mediated transfection by volume reduction and centrifugation Biotechniques 25(1): 46-49. Impact Factor: 2.3: Citation: 15
  79. Taichman R.S., Reilly M.J., Verma R.S., and Emerson S.G. (1997) Augmented production of interleukin 6 by normal human osteoblasts in response to CD34+ hematopoietic bone marrow cells in vitro Blood 15: 89(4), 1165 1172. Impact Factor: 10.37: Citation: 54
  80. Natarajan V., Vepa S., Verma R. S., and Scribner W. M. (1996) Role of Protein Tyrosine Phosphorylation on H202 lnduced Phospholiase D Activation of Endothelial Cells Phospholipase D. American J. Physiol 271 (3Pt1) L400 L408. Impact factor: 0.88: Citation: 62
  81. Verma, R. S., and Antony, A. C. (1992) Immunoreactive folate binding proteins from human saliva: isolation and comparison of two distinct species. Biochem. J. 286: 707 715. Correction Biochem J 289: 927 928. (1993) Impact Factor: 4.349: Citation: 10
  82. Verma R. S., Gullapalli, S., and Antony, A. C. (1992) Evidence that the hydrophobicity of isolated in situ and de novo synthesized native human placental folate receptor is a function of glycosylphosphatidylinositol anchoring to membranes. J. Biol. Chem. 267:4119 4127. Impact Factor: 7.66: Citation: 59
  83. Verma R. S., and Antony, A.C. (1991) Kinetic analysis, isolation and characterization of hydrophilic folate binding protein released from chorionic villi cultured under serum free conditions. J. Biol. Chem. 266:12522 12535. Impact Factor: 7.66: Citation: 10
  84. Verma R. S., and Antony, A. C. (1991) Kinetic isolation and characterization of soluble (s) folatebinding protein (flop) released from human placental chorionic villi associated hydrophobic FBP (M FBP) in serum free culture. Clinical Research, 39(2): 205a Impact Factor: 0.159:
  85. Antony, A. C., Briddell, R. A., Brandt, J. E., Straneva, J. E., Verma R. S., Miller, M. E., Kalasinski, L. A., and Hoffman, R. (1991) Megaloblastic hematopolesis in vitro: interaction of anti folate receptor antibodies with hematopoletic cells leads to a proliferative response independent of megaloblastic changes J. Clin. Invest. 87: 313 325. Impact Factor: 10.92: Citation: 21
  86. Antony, A. C., Kane, M., Kincade, S., Briddell, R., and Verma R. S. (1989) Folate (pteroylglutamate) uptake in human erythrocytes, erythroid precursors and kb cells at high extra cellular folate concentrations: evidence against a specific folate binding and transport protein. Biochem. J. 260:401- 411. Impact Factor: 4.349: Citation: 22
  87. Antony, A. C., Verma R. S., Unune, A. R., and Larosa, J. A. (1989) Identification of hydrophobic folate binding forms. J. Biol. Chem. 264:1911 1914. Impact Factor: 7.66: Citation: 32
  88. Antony, A. C., and Verma R. S. (1989) Hydrophobic erythrocyte folate binding proteins are converted to hydrophilic forms by trypsin in vitro. Biochem. Biophys. Acta. 979:62 68. Impact Factor: 2.49: Citation: 6
  89. Verma R. S., Kincade, R. S., and Antony, A. C. (1988) Isolation and characterization of two distinct immunoreactive folate binding proteins from human saliva. Clinical Research. 36(3): 360. Impact factor: 0.195: Citation: 37
  90. Antony, A. C., Bruno, E., Briddell, R., Brandt, J., Verma R. S., and Hoffman, R. (1987) Effect of perturbation of specific folate receptor during in vitro erythropoiesis. J. Clin. Invest. 80(6): 1618 1623. Impact Factor: 10.92: Citation: 34
  91. Panday, R., Verma R. S. and Khullar, G. K. (1987) Effect of choline, ethanolamine and serine supplementation on the membrane properties of mycosporum gypsum. Lipids. 22(7): 530 534. Impact Factor: 2.040
  92. Antony, A. C., Bruno, E., Bridell, R., Brandt, J., Verma R. S., and Hoffman, R. (1987) Evidence for a role for folate receptor during in vitro erythropolesis. Clinical research 35(3): 569. Impact Factor: 0.195
  93. Antony, A. C., Kincade, S., Verma R. S., And Krishnan, S. R. (1987) Identification of high affinity folate binding protein in human erythrocyte membrane. J. Clin. Invest. 80:711 723. Impact Factor: 10.92: Citation: 31
  94. Verma R. S., Spencer martin, I., and Van uden, N. (1987) Role of de novo protein synthesis in the inter conversion of glucose transport systems in the yeast Pichia ohmeri. Biochem. Biophys. Acta. 900:139 144. Impact Factor: 2.49: Citation:22
  95. Antony, A. C., Verma R. S., and Knicade, R. S. (1987) Development of a specific radio immunoassay of’ the placental folate receptor and related high affinity folate binding protein in human tissues. Anal. Biochem. 162:224 235. Impact Factor: 2.149: Citation: 10
  96. Verma R. S., Rao, T. V. G., and Prasad, R. (1984) An inducible, specific and derepressible transport of L series in saccharomyces cerevisiae. Biochem. Biophys. Acta. 778:289 297. Impact Factor: 2.59: Citation: 13
  97. Verma R. S. (1984) Amino Acid Transport in Yeast. Ph.D. Thesis Jawaharlal Nehru University New Delhi 110067, India
  98. Rao, T. V. G., Verma R. S., and Prasad, R. (1983) Transport of purine, pyrimidine bases and nucleosides in candida albicans, a pathogenic yeast. Biochem. Int. 6:409 416. citation: 12
  99. Verma R. S., and Prasad, R. (1983) Absence of depression of amino acids transports in candida. Biochem. Int. 7:707 717. Citation: 8
  100. Prasad, R., Jayakumar, A., Singh, M., Trivedi, A., Khare, S., Verma R. S., Rao, T. V. G., and Dudani, A. K. (1983) Amino acid transport in yeast. In: proceedings of symposium on the role biochemistry in harnessing the environment, Indian Toxicological Research Center, Lucknow, India 8 (No. 1 2), Pp. 31 43.
  101. Verma R. S., and Prasad, R. (1983) Amino acid transport in whole cell and membrane vesicles of saccharomyces cerevisiae. In: proceedings of viii international specialized symposium on yeast, Baroda, India.
  102. Verma R. S., and Prasad, R. (1983) Characteristics of amino acid transport in deficient (rhoO) mutant cells. Ind. J. Biochem. Biophys. 20:104 109. Impact Factor: 0.45 Citation: 1
  103. Jayakumar, A., Singh, M., Verma R. S., Baquer, N. Z., and Prasad, R. (1981) Characteristics of proline transport in the spheroplasts from candida albicans cells. Ind. J. Biochem. Biophys. 1 8:206 210. Citation: 8

General, social and ethical topic

  1.   Rama S Verma and Sreejit P (2009) Culture and Morality Bulletin Chennai Academy for Science, Humanities and Religion 2(2) July 2009
  2.   Rama S Verma, Bijesh K. Biswal. Abhilasha, Chithra R and Sugapriya D. M. (2009) Innovation and Challenges in Biotechnology (ICICB-08) ISBN: 978-93-.80043-16-6

Text Books/ Monographs Authored/ Book Chapter

  1. Jahnavi Sarvepalli, Rajalakshmi Santhakumar and Rama Shanker Verma (2015) Evolving Concepts for Use of Stem Cells and Tissue Engineering for Cardiac Regenerationin Optimizing Assistive Technologies for Aging Populations Eds Morsi M, Shukla A and Rathore CP – A volume in the Advances in Medical Technologies and Clinical Practice (AMTCP) BookSeries IGI publication DOI: 10.4018/978-1-4666-9530-6.ch011
  2. Sithambaram Devilakshmi, Jayaprakasam Madhumathi and Rama Shanker Verma (2015) Immunotoxins, Resistance and Cancer Stem Cells: Future Perspective Resistance to Immunotoxins in Cancer Therapy (2015) Edited By Rama S Verma ISBN 978-3-319-17274-3 Springer Switerland
  3. Sreejit Parmeswaran, Rajlakshmi Santhakumar, Prasanna vidyasekar and Rama S Verma (2015) Enrichment of Cardiomyocytes in primary cuture of Neonatal heats Cardiomyocytes: Methods and Protocols (Methods in Molecular Biology) Springer Protocols: Editors Gary R Skuse and Maureen C Ferran ISBN-13: 978-1493925711 Human Press USA
  4. Pavithra Shyamsunder, Rama S. Verma, Sudit S. Mukhopadhyay and Alex Lyakhovich (2015) Involvement of Mitochondria in the Pathology of Fanconi Anemia Fanconi Anemia and Oxidative Stress: Mechanistic Background and Clinical Prospects ed by Nova Science Publisher USA
  5. Rama Shanker Verma, Sirisha Potala, Mrudula Mathew and Swati chaudhary (2012) Application of Microbial Toxins for Cancer Therapy T. Satyanarayana et al. (eds.), Microorganisms in Sustainable Agriculture and Biotechnology, DOI 10.1007/978-94-007-2214-9_28, © Springer Science Business Media B.V. 2012
  6. Prasanna Vidyasekar, Pavithra Shyamsunder, and Rama S Verma (2010) Nano-biotechnology: A new generation of biomedicine-Innovative nanotechnology in key areas of biomedical engineering and cancer therapy “Application Nanotechnology for Human Health” 2 (2), 237-254 by Dr. Sanjeeb K SahooPublisher CRC Press, Taylor and Francis Group Florida USA
  7. Rama S Verma, Abhilasha, Sugapriya M. D. and Chithra R. (2009) Animal biotechnology: application and potential risks in Biotechnology in Functional Foods and Nutraceuticals 14, 220- 250, Editor – Dr. Debasis Bagchai publisher- Taylor and Francis USA
  8. Denis English, Akshay Anand, Rama S. Verma and Stephan Gluck (2009) Neural Stem Cells: New Hope for Successful Therapy) Stem Cell and Regenerative Medicine, 8, 129-151 Editor- Dr. Herman S. Cheung (Ed.) Bentham Science Publishers Ltd. USA
  9. Prasanna Vidyasekar, Pavithra Shyamsunder, and Rama S Verma (2010) Nano-biotechnology: A new generation of biomedicine-Innovative nanotechnology in key areas of biomedical engineering and cancer therapy “Application Nanotechnology for Human Health” Ed. by Dr. Sanjeeb K Sahoo) Publisher – Pan Stanford, Italy (in Press)
  10. Rama Shanker Verma, Sirisha Potala, Mrudula Mathew and Swati chaudhary (2012) Application of Microbial Toxins for Cancer Therapy T. Satyanarayana et al. (eds.), Microorganisms in Sustainable Agriculture and Biotechnology, DOI 10.1007/978-94-007-2214-9_28, © Springer Science Business Media B.V. 2012
  11. Verma R.S. (2006) “Targeting Human growth factors, cytokines gene into Silkworms Muga silkworm” in Biochemistry, Biotechnology and Molecular Biology, Published at RRL Jorhat pp 204-211.