Dr. Madhulika Dixit
Madhulika Dixit received her PhD from IIT Bombay in molecular biology by studying transcriptional regulation of extracellular protease gene epr in Bacillus subtilis. She then continued her interest in molecular and cellular biology to understand cardiovascular complications at the Department of Physiology, University of Tennessee Health Science Center, Memphis, USA. There she was involved in characterizing the effect of chronic hyperinsulinemia on responses of smooth muscle cells towards anti-atherogenic agent nitric oxide. She then extended her interest in understanding endothelial behavior in response to fluid shear stress at the Institute of Cardiovascular Physiology, Goethe University, Frankfurt am Main, Germany.
She has been at IIT Madras since 2007. Her research interests are to understand molecular triggers, which initiate vascular dysfunction in insulin resistance and diabetes. In order to get a holistic picture her group subscribes to following approaches:
- In vitro primary cell cultures of aortic smooth muscle cells (SMC), human umbilical vein derived endothelial cells (HUVECs) and endothelial progenitor cells (EPCs).
- Cell and molecular biology techniques and use of RNA interference and viral vectors for pathway characterizations.
- Screening of clinical samples for scoring changes in gene expression through micro-array analysis.
- Validation of in vitro data through in vivo animal experiments.
- PhD (Molecular Biology), Indian Institute of Technology Bombay
- MSc (Life Sciences), University of Mumbai
- Assistant Professor, IIT Madras (2007-Present)
- Head, Vascular Biology Division, MDRF Chennai (2006-2007)
- Senior Scientist, Institute of Cardiovascular Physiology, Frankfurt am Main, Germany (2003-2006)
- Post doctoral Fellow, UT Health Science Center, Memphis, USA (2001-2003)
- Senior IYBA, DBT, Government of India, 2010
- Innovative Young Biotechnologist Awardee, DBT, Government of India, 2006
- Senior Research Fellow
- Junior Research Fellow
- Molecular and Cellular Biochemistry
- Biochimie
- Diabetes Care
- Member- American Society of Cell Biologists.
- Member- European Vascular Genomics Network
- Member- Research Society for the Study of Diabetes in India
- Since 1996 have been involved in training under-graduate and graduate students. Courses Taught include:
- Biochemistry and Metabolism
- Laboratory courses in Biochemistry and Molecular Biology for B.Tech, M.Sc and M.Tech students.
- Laboratory Course in Microbiology for B.Tech, M.Sc and M.Tech students at IIT Bombay.
- At IIT Madras:
- BT3010: Cell Biology (Core Course for B.Techs)
- BT2020: Biochemistry (Core Course for B.Techs)
- BT3110: Molecular Biology and Genetic Engineering Lab.
- BT6901: Vascular Biology (Elective for MS and PhD students).
- Institute Open House 2008 Department Coordinator.
- Setting up of disposal of Bio-medical waste in the Department.
- Coordinator of Common Equipment Rooms (2008-2010).
- Faculty In-charge of Tissue Processing Lab (Room: 512).
- Instructor of iGEM2009 IIT Madras Team, which participated in MIT, USA.
- Institute M Tech Task Force Member (2011)
- Member of PhD selection committee (since August 2011)
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