We aim to understand how genetic and environmental factors influence biological systems by studying genotype-phenotype relationships in yeast using systems genetics approaches.
We leverage data science and AI to predict adverse health outcomes & enhance patient care in maternal & child health.
Kamaraj, V, Sinha, H* (2024). "SCI-VCF: a cross-platform GUI solution to summarize, compare, inspect and visualize the variant call format", NAR Genomics and Bioinformatics, 6, pp. lqae083, DOI: 10.1093/nargab/lqae083.
Palanikumar I, Sinha H, Raman K* (2024). "Panera: A novel framework for surmounting uncertainty in microbial community modelling using pan-genera metabolic models", iScience, 27, pp. 110358, DOI: 10.1016/j.isci.2024.110358.
Gadekar VP, Damaraju N, Xavier A, Thakur SS, Vijayram R, Desiraju BK, Misra S, GARBH-Ini Study Group, Wadhwa N, Khurana A, Rathore S, Abraham A, , Rengaswamy R, Benjamin S, Cherian AG, Bhatnagar S, Thiruvengadam R*, Sinha H* (2024). "Development and external validation of Indian population-specific Garbhini-GA2 model for estimating gestational age in second and third trimesters", The Lancet Regional Health Southeast Asia , 25, pp. 100362, DOI: 10.1016/j.lansea.2024.100362.
Chaithanya, KV, Sinha H* (2023). "MKT1 alleles regulate stress responses through post-transcriptional modulation of Puf3 targets in budding yeast", Yeast, 40, pp. 616, DOI: 10.1002/yea.3908.
Kovuri P, Yadav A, Sinha H* (2023). "Role of genetic architecture in phenotypic plasticity", Trends in Genetics, 39, pp. 703, DOI: 10.1016/j.tig.2023.04.002.
Vijayram R, Damaraju N, Xavier A., Desiraju B.K., Thiruvengadam R., Misra S., Chopra S., Khurana A, Wadhwa N, Garbh-Ini Study Group, Rengaswamy R, Sinha H*, Bhatnagar S* (2021). "Comparison of first trimester dating methods for gestational age estimation and their implication on preterm birth classification in a North Indian cohort", BMC Pregnancy and Childbirth, 21, pp. 343, DOI: 10.1186/s12884-021-03807-4.
