Department of Biotechnology | Indian Institute Of Technology Madras , Chennai
team

N Manoj

Professor

Ph.D., Indian Institute of Science

M.Sc., University of Mysore

Block 1, BT 304

044 2257 4113

nmanoj[at]iitm[.]ac[.]in

Lab: Block 1, BT 309

Lab: 044 2257 5100

Lab Website
Scopus
Google Scholar

  • Structural biochemistry of hydrolases
  • Protein structure and function
  • Computational molecular evolution
  • Bioinformatics

  1. Chandel, S., Manikandan, A., Mehta, N.,Nathan, Abel Arul.,Tiwari, Rakesh Kumar.,Mohapatra, Samar Bhallabha.,Chandran, Mahesh.,Jaleel, Abdul., Manoj, N., Dixit, M. (2021). "The protein tyrosine phosphatase PTP-PEST mediates hypoxia-induced endothelial autophagy and angiogenesis via AMPK activation", Journal of Cell Science, 134(1), pp. jcs250274, DOI: 10.1242/jcs.250274.
  2. Mohapatra, S.B., Manoj, N. (2021). "Structural basis of catalysis and substrate recognition by the NAD(H)-dependent α-dglucuronidase from the glycoside hydrolase family 4", Biochemical Journal, 478(4), pp. pp. 943–959, DOI: 10.1042/BCJ20200824.
  3. Garg, P., Manoj, N. (2023). "Structure of an iminosugar complex of a glycoside hydrolase family 5 lichenase provides insights into the active site", Biochimie, 204, pp. pp. 69–77, DOI: 10.1016/j.biochi.2022.09.001.
  4. Mohapatra, S.B., Manoj, N. (2023). "Overview of structure-function relationships of glucuronidases", Glycoside Hydrolases: Biochemistry, Biophysics, and Biotechnology, , pp. 255–278, DOI: 10.1016/B978-0-323-91805-3.00015-0.
  5. Manikandan, A., Sreevidya, T.S., Manoj, N., Vemparala, S., Dixit, M. (2023). "In-silico identification of Tyr232 in AMPKα2 as a dephosphorylation site for the protein tyrosine phosphatase PTP-PEST", Proteins: Structure, Function and Bioinformatics, 91(6), pp. pp. 831–846, DOI: 10.1002/prot.26470.