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Centres and Facilities

Major Center

Centre of Excellence in Bioprocess Engineering

National Centre for Cellular Dynamics

Program Support in Cancer Biology

Confocal Microscope

Model : FV3000

Brand : Olympus

The FluoView3000 confocal microscope is a powerful tool for imaging in a variety of research applications. It is a confocal laser scanning microscope, which means that it uses a laser to scan a sample and only detect light that is emitted from the focal plane.

Drop shape analyser

Model : DS25B

Brand : KRUSS

The drop shape analyser is used for wetting and adhesion analysis. The instrument can be used to determine the contact angle between a liquid and a solid and also to measure surface free energy. It is especially useful for the analysis of cleaned, pre-treated or coated solid materials.

Flow Cytometry Facility

Model : FACS Aria III and FACS Calibur

Brand : BD

Flow cytometry is a technology that helps in the analysis of single cells in suspension. Flow cytometers utilize lasers as light sources to produce both scattered and fluorescent light signals that are read by detectors such as photodiodes or photomultiplier tubes. These signals are converted into electronic signals that are analyzed by a computer and written to a standardized format (.fcs) data file. Cell populations can be analyzed and/or purified based on their fluorescent or light scattering characteristics.

Fluorescence Microscope

Model : IX51

Brand : OLYMPUS

The IX51 inverted system microscope addresses the observation and imaging needs of high-level laboratory and clinical applications. Modular design and the excellence of its optical system serve tasks from cell culture observation to fluorescence microscopy. Superior frame stability, ergonomic layout and low-positioned controls make the IX51 the user-friendly microscope for high-volume laboratories. Efficient operation is complemented by an unobtrusive long working distance condenser and adjustment-free 30W halogen illumination.

Inverted Fluorescence Microscope

Model : IX83

Brand : Olympus

The IX83 is a versatile and powerful inverted fluorescence microscope designed for a wide range of research applications, including live cell imaging, drug discovery, and cell biology. Its two-deck system enables high-speed, fully automated device selection and advanced image acquisition, making it an ideal choice for demanding research protocols.

Lambda 35 UV-Vis spectrophotometer

Model : Lambda 35

Brand : Perkin Elmer

PC control is provided via UV WinLab 6.4 Software and a new Windows 10 PC/Monitor.UV WinLab software guides you through a step-by-step process that simplifies analysis from sample entry to report generation, eliminating costly mistakes and delivering rapid results.

LCMS

Model : Orbitrap Elite

Brand : Thermo Fisher Scientific

Chromatography and Mass Spectrometry-Orbitrap Elite: Thermo Scientific Orbitrap Elite Mass spectrometer has a dual pressure linear ion trap coupled with high-field Orbitrap Mass analyzer facilitating increased sensitivity, reliability and dynamic range for better detection and MSn identification.

Microplate spectrophotometer

Model : Epoch

Brand : Biotek instruments

Epoch microplate spectrophotometer has monochromator-based optics, for a filter-free, wide wavelength range for UV-Vis absorbance measurements. Epoch is controlled with the Gen5 software interface, with simple programming and powerful data analysis. This robust, low maintenance microplate absorbance reader is a cost-effective system. Reliability and ease of use ensure time savings in laboratory workflows.

Microplate spectrophotometer

Model : xMark

Brand : Biorad

With its unique imaging capabilities, monochromator design, and spectral scanning feature (which eliminates the need for filters), the xMark™ Microplate Absorbance Spectrophotometer can find the best wavelength within a broad range for any photometric application. The xMark Spectrophotometer is also flexible enough to read all standard microplates, from 6- to 1,536-well formats. Using Microplate Manager® Software, the xMark Spectrophotometer can perform a wide range of end-point and kinetic applications with spectral scanning within low UV to infrared wavelengths. Extensive data analysis includes comprehensive curve-fit models and automated data export in single-plate or batch formats.

Muffle furnace

Model : SIGMA

Brand : SIGMA

Muffle furnaces have double walled insulated doors mounted on heavy duty hinges and are provided with effective locking arrangements. The temperature of muffle furnace is maintained and controlled by a digital temperature controller working in conjunction with a thermocouple placed in the hot zoneSupplied complete with control panel.

The DS-11 Series of Spectrophotometer/Fluorometers from DeNovix and the NanoDrop™ One Spectrophotometer are both used to perform fast quantification of nucleic acids and proteins. The spectrophotometer/fluorometer range from DeNovix provides superior limits of detection, the widest dynamic range, an easy-to-use interface and powerful networking features, which surpass the capabilities of the NanoDrop™ Spectrophotometer. Here we will outline the difference between the DeNovix DS-11 FX Spectrophotometer/Fluorometers and the NanoDrop™ One Spectrophotometer.

Probe Sonicator

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Brand :

Devices employing ultrasonic waves to homogenize samples, particularly cells/subcellular structures in suspension; also includes accessories and support devices such as power options, probes, sound enclosures, and more.Sonication uses sound waves to disrupt substances. An electrical signal is converted into a vibration that can mix solutions, dissolve solids into liquids, and remove dissolved gas from liquids. When sound waves at ultrasonic frequencies (>20 kHz) are used, the process is called ultrasonication.

Real Time PCR

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Brand :

The Applied Biosystems® QuantStudio™ 7 Flex Real-Time PCR System is a useful system in research which enables a broad range of real-time PCR-based applications through its multiplexing capabilities and interchangeable block formats. With a simplified workflow, intuitive software, automation capabilities, and touch-screen interface, the QuantStudio™ 7 Flex system offers exceptional reproducibility with minimal well-to-well and instrument-to-instrument variation.

Spin coating system

Model : SpinNXG-P1

Brand : APEX INSTRUMENTS

The high range of speed, duration and acceleration allow the user to adjust the parameters according to his requirements. Spin coaters need to deposit thin films on the substrate, so high speed and acceleration help a lot in carrying out a wide range of tests.

Thermal cycler

Model : NEXUS GRADIENT

Brand : EPPENDORF

Mastercycler nexus is your reliable companion when it comes to the daily routine of PCR.Flexlid Concept:Due to the flexlid concept, the cycler can deal with all types of PCR consumables, from low volume all the way up to 0.5 mL PCR tubes. Of course, all common PCR plates fit – and if your throughput becomes even higher, you can just connect one or two Mastercycler nexus eco to your Mastercycler nexus.Gradient with SteadySlope® technology The gradient option of the Mastercycler pro features the SteadySlope® technology to ensure that the heating and cooling ramp rates are identical in both gradient and normal operation. Thus, you can expect identical temperature control characteristics in both optimization and routine experiments. Programming the gradient with the Control Panel and the CycleManager pro is easy and intuitive.

Ultracentrifuge

Model : Optima™ XL-100 K

Brand : Beckman

The Beckman OptimaTM XL-100K Ultracentrifuge operates at very high speed of upto 100,000 rpm at up to 802,000 g with a 100 Ti rotor. The equipment is equipped with an imbalance-tolerant drive which protects against small operator mistakes, and offers an energy-efficient consumption and heat output system. The software is advanced and it is easy to use with a push-button operation system and a touch-key control panel which enables easy handling. Also the energy-efficient and environment-friendly air-cooled drive eliminates any harmful coolants like CFC. A key interlock switch helps normal, locked or zonal operation. The important features of the Ultracentrifuge are its very high speed of 100000 rpm with a maximum RCF of 802000 g.

Universal Testing Machine

Model : Tinius olsen

Brand : 1ST

The 1ST is designed for tension, flexure and shear strength testing on materials and assemblies. The robust design that incorporates quality materials and components ensures that our reputation for superior system performance, ease of use, and longevity is maintained. A variety of load cells are available at differing capacities that give precise applied load measurements from the smallest test specimen to ones that go to full machine capacity. Test machines become complete, powerful test systems with the addition of grips to hold the specimen, strain measurement instrumentation and Tinius Olsen’s Horizon software.

Gamma Irradiation Chamber

Model : BI-2000

Brand : BRIT

Department of Biotechnology at IIT Madras has the state-of-the-art Gamma Irradiation Chamber facility exclusive for research and development. The equipment has the capacity to provide a radiation dose of 10.77 gy/minute.We offer irradiation services to both biological (cell lines and mice etc) and non-biological samples (polymers and elemental materials etc) on payment basis. Irradiation projects involving mice and other mammalian model systems are taken only upon producing valid Institutional Animal Ethics Committee (IAEC) approval from the respective institutions.Our services are open to other departments&centres at IIT Madras, other educational &research institutions and industries as well.